Tablet press work possible problems and solutions in the process

Tablet press problems that may occur in the process of work, share with you a Jin Zong medicine machine small make up today press piece of work may occur in the process of problem analysis and solution; First: tablet press release: pressing after tablets, hardness is not enough, the surface has a hole, with finger gently pressure, fracture, namely the reason analysis and solution: 1, raw material grinding fineness, fibrous or elastic material or uneven oil component content and more mixed. Drugs can be shattered through 100 mesh sieve, choose the viscosity strong adhesive, increasing the pressure of the tablet press, increase oil drug absorption agent fully blending method to overcome it. 2, glue or insufficient dosage of wetting agent or improper selection, make irregular particle texture osteoporosis or particle size distribution, coarse and fine particle layer. Can choose appropriate adhesive or increase consumption, improve the granulating process, mixing soft material, mix both particles such as methods to overcome it. 3, grain moisture content is too little, too dry, containing water of crystallization of material particles of losing more water of crystallization in grain drying process, make the particles crunchy, easy to loose lobes. So when granulating, according to the different species should be controlled grain moisture content. Works such as made of particles is too, can be sprayed into the proper amount of dilute ethanol ( 50% - 60%) And tablet after blending. 4, particle illiquid, fill in the die hole uneven granules. 5, there are relatively large, particles or debris blocking grain scraper and the feed opening, filling quantity. Six factors, pelleting machine. Pressure is too small, stamping machine more punch length not neat, speed too fast or waxing in the feed hopper particles. Adjustable pressure, check whether the die is supporting complete, adjust the speed, qijia particles to keep inside the hopper overcome certain methods such as stock. Second: tablet press lobes: tablet by vibration or by placing a split from the waist are called lumbar fracture; Split from the top as the top crack, crack and the crack top always called lobes, causal analysis and resolution methods: 1, the material itself is elastic, the fibrous material or for oilseed composition more. Powdered sugar can be added to reduce the fiber flexibility, strengthen the bonding effect or increase oil absorbent material, fully mixing after tabletting. 2, glue or improper wetting agent or improper dosage, particles on pressure were poor adhesion. 3, too dry, containing water of crystallization material loss caused by too much lobes, solution and loose pieces of the same. 4, some crystalline materials, without sufficient crushing. These drugs can be fully after granulating. 5, excess powder, lubricant, lobes, caused by too much powder in the air can't escape in time by pressure within the tablet, when lifting pressure, tablet internal air expanding lobes, can sieve to partial fine powder and decrease the dosage of lubricant to overcome them. 6, tablet press stress, strength and lobes; Speed too fast or die do not conform to the requirements, the punch length, wear in the middle, the department is greater than the top and bottom or punch to the inner edge, all can make lobe was caused when the tablet out. Adjustable pressure and speed, and improve the punching die, check the switch in a timely manner. 7, tabletting low room temperature, low humidity, easy cause lobes, especially the viscosity difference drugs easy to produce. The air-conditioning system can be solved. Tablet press these problems solved, can the normal work, run.